Lack of clastogenic effects of L-thyroxine in whole-blood cultured human lymphocytes
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چکیده
منابع مشابه
Lack of clastogenic effects of L-thyroxine in whole-blood cultured human lymphocytes
Thyroid hormones stimulate aerobic metabolism which may lead to oxidative stress accompanied by damage to various cellular macromolecules, including DNA. Previous comet assay studies have shown that thyroid hormones cause DNA damage due to the creation of reactive oxygen species (ROS). However, cytogenetic studies have been equivocal because although an increase in the sister-chromatid exchange...
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Baccharis dracunculifolia De Candole (DC) (Asteraceae) is indigenous throughout southeastern Latin America and is used by local people in traditional medicine. This plant is known to be the source of resin for the highly valued Brazilian green propolis. As no information is available on the safety of high doses of B. dracunculifolia extract, we evaluated the mutagenic potential of high doses of...
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ژورنال
عنوان ژورنال: Genetics and Molecular Biology
سال: 2007
ISSN: 1415-4757
DOI: 10.1590/s1415-47572007000600019